Pancreatic cancer is relatively uncommon, with a lifetime risk of ~1.5% for individuals in the United States. For the majority of pancreatic cancers, the cause is unknown and there is no known family history of the disease. In these circumstances, a cancer is...
A woman’s physician ordered multi-gene panel testing due to her family history of cancer and told her that the lab had found two “errors” in the PALB2 gene. Compared to the general population, patients with a pathogenic variant in PALB2 have between...
Many supposed breast cancer risk genes don’t raise risk, studies find By Marie McCullough for The Philadelphia Inquirer In the quarter century since the watershed discovery of BRCA1 and BRCA2, dozens of other genes have been implicated in hereditary breast cancer. A...
A 42-year-old woman underwent a breast biopsy due to an abnormal mammogram. Even though the biopsy analysis yielded benign findings, the woman’s family history with pancreatic cancer prompted the surgeon to order a 70-gene panel test to assess if she had...
