APC

The Genetics of Pancreatic Cancer: Part 1

Posts Tagged ‘APC’

The Genetics of Pancreatic Cancer: Part 1

In recognition of Pancreatic Cancer Awareness Month we’ve compiled information about inherited forms of pancreatic cancer.  As you may know, pancreatic cancer is relatively uncommon, with a lifetime risk of ~1.5% for individuals in the United States.  For the majority of pancreatic cancers the cause is unknown and there is no known family history of…

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Recessive Mutations in MSH3 Found to Cause Colon Cancer

A research team at the University of Bonn in Germany has published a new study regarding  a mismatch repair gene called MSH3.  This discovery is unique in that MSH3 is 1) inherited in an autosomal recessive pattern and 2) causes the development of multiple colon polyps, which is in contrast to most other known mismatch…

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Beyond BRCA: Gardner's Syndrome (FAP)

This is the second in a series of articles built to highlight rare hereditary cancer syndromes. This is Elizabeth’s story of living with FAP, also known as Gardner’s Syndrome. Genetic Counseling Note: There are several hereditary cancer syndromes that can cause affected individuals to develop multiple polyps in their gastrointestinal (GI) tracts. One of these…

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I Had a Cancer Gene Panel Done and All I Got Was This T-shirt

Over the past 15 years we’ve learned that there are many hereditary cancer genes that, when mutated, increase the risk of cancer development. Not just BRCA1 and BRCA2 for hereditary breast and ovarian cancer. Not just the Lynch Syndrome genes and APC for hereditary colon cancer. Dozens of genes that, when mutated, cause different ranges…

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No, You’re Too Young to Have Colon Cancer

The vast majority of people who are diagnosed with colon cancer are over the age of 50. In fact, the average age of colon cancer diagnosis in the United States is 72. However, colon cancer can and does occur in people in their teens, twenties, thirties and forties. These ages of diagnosis are typical in people…

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