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Confusion Over Colon Cancer Syndromes Leads to Wrong Testing

Confusion Over Colon Cancer Syndromes Leads to Wrong Testing

by Caitlin Kingsley | Feb 24, 2020 | Genetic Testing Challenges in Oncology, News

During a visit with a new primary care physician, a 45-year-old man told his doctor that he had a family history of cancer and Lynch syndrome, a hereditary condition that increases the risk for colon, uterine, and other cancers. He also recounted that he had tested...
Despite Barriers, Labs Starting to Report Suspected Cancer Risk Mutations Seen in Tumor Testing

Despite Barriers, Labs Starting to Report Suspected Cancer Risk Mutations Seen in Tumor Testing

by Caitlin Kingsley | Feb 6, 2020 | News

Paired tumor/germline testing is far from standard practice in cancer care, but some experts in the field are advocating that when patients have their tumors genomically profiled to determine precision medicine options, that is an opportunity to also evaluate them for...
A Genetic Counselor’s Take on Why America Should Not Collect DNA From Migrants

A Genetic Counselor’s Take on Why America Should Not Collect DNA From Migrants

by Caitlin Kingsley | Jan 31, 2020 | News

Last week, three House Democrats called on the Department of Homeland Security (DHS) to stop collecting DNA from migrants in government custody. Democratic Reps. Rashida Tlaib (MI), Veronica Escobar (TX), and Congressional Hispanic Caucus...
Mirror, Mirror, On the Wall: The Epigenetics of Aging

Mirror, Mirror, On the Wall: The Epigenetics of Aging

by Caitlin Kingsley | Jan 24, 2020 | News

A few months ago, I received an email from a company called Chronomics that tests for epigenetic changes in your DNA. I’m still a bit scarred from my personal direct-to-consumer testing experience, so I was initially reluctant to explore yet another genetic...
Patient Told Genetic Test Was Negative Turns Out to Be MAP Carrier

Patient Told Genetic Test Was Negative Turns Out to Be MAP Carrier

by Caitlin Kingsley | Jan 21, 2020 | Genetic Testing Challenges in Oncology, News

A 49-year-old woman with a maternal family history of breast cancer was seen in a high-risk breast clinic. Both her mother and grandmother had breast cancer at an early age. Because her mother had reportedly declined genetic testing, the woman’s OB/GYN had...
With More Than a Million Records, ClinVar Value Grows as Variant Classification Resource

With More Than a Million Records, ClinVar Value Grows as Variant Classification Resource

by Caitlin Kingsley | Jan 9, 2020 | News

Since its launch in 2013, ClinVar has not only amassed a wealth of genetic variant information, but the lab and clinical genetics community in the US are readily referencing it when they have questions about the clinical significance of variants. A few healthcare...
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