During a visit with a new primary care physician, a 45-year-old man told his doctor that he had a family history of cancer and Lynch syndrome, a hereditary condition that increases the risk for colon, uterine, and other cancers. He also recounted that he had tested...
Paired tumor/germline testing is far from standard practice in cancer care, but some experts in the field are advocating that when patients have their tumors genomically profiled to determine precision medicine options, that is an opportunity to also evaluate them for...
Last week, three House Democrats called on the Department of Homeland Security (DHS) to stop collecting DNA from migrants in government custody. Democratic Reps. Rashida Tlaib (MI), Veronica Escobar (TX), and Congressional Hispanic Caucus...
A few months ago, I received an email from a company called Chronomics that tests for epigenetic changes in your DNA. I’m still a bit scarred from my personal direct-to-consumer testing experience, so I was initially reluctant to explore yet another genetic...
A 49-year-old woman with a maternal family history of breast cancer was seen in a high-risk breast clinic. Both her mother and grandmother had breast cancer at an early age. Because her mother had reportedly declined genetic testing, the woman’s OB/GYN had...
Since its launch in 2013, ClinVar has not only amassed a wealth of genetic variant information, but the lab and clinical genetics community in the US are readily referencing it when they have questions about the clinical significance of variants. A few healthcare...
